Ryan Gaudet

Work

Columbia University Vagelos College of Physicians and Surgeons

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Assistant Professor

US

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Howard Hughes Medical Institute

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Postdoctoral Fellow

US

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Education

Yale University

United States of America
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Postdoctoral Fellow

University of Toronto

Canada
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PhD

University of Manitoba

Canada
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MSc

University of Prince Edward Island Charlottetown

Canada
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BSc (Hon)

Publications

Temperate phages enhance host fitness via RNA-guided flagellar remodeling

preprint

The antibacterial factor APOL3 couples lysosomal damage to mitochondrial DNA efflux and type I IFN induction

BioRxiv

preprint

PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection

Nature

journal-article

Human XIRP1 is a macrophage podosome protein utilized by Listeria for actin-based motility

preprint

A human apolipoprotein L with detergent-like activity kills intracellular pathogens.

Science (New York, N.Y.)

journal-article

A human apolipoprotein L with detergent-like activity kills intracellular pathogens

Science

journal-article

The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling.

Science (New York, N.Y.)

journal-article

High-Throughput Screening Identifies Genes Required for Candida albicans Induction of Macrophage Pyroptosis.

mBio

journal-article

TIFA Signaling in Gastric Epithelial Cells Initiates the cag Type 4 Secretion System-Dependent Innate Immune Response to Helicobacter pylori Infection.

mBio

journal-article

Innate Recognition of Intracellular Bacterial Growth Is Driven by the TIFA-Dependent Cytosolic Surveillance Pathway.

Cell reports

journal-article

Evolution of Cell-Autonomous Effector Mechanisms in Macrophages versus Non-Immune Cells.

Microbiology spectrum

journal-article

Heptose Sounds the Alarm: Innate Sensing of a Bacterial Sugar Stimulates Immunity.

PLoS pathogens

journal-article

Heptose Sounds the Alarm: Innate Sensing of a Bacterial Sugar Stimulates Immunity

PLOS Pathogens

journal-article

Cytosolic detection of the bacterial metabolite HBP activates TIFA-dependent innate immunity.

Science (New York, N.Y.)

journal-article

Neisseria gonorrhoeae-derived heptose elicits an innate immune response and drives HIV-1 expression.

Proceedings of the National Academy of Sciences of the United States of America

journal-article

Antibodies in infectious diseases: polyclonals, monoclonals and niche biotechnology.

New biotechnology

journal-article

Molecular characterization of the cervical and systemic B-cell repertoire: Unique, yet overlapping, immune compartments of an HIV-1 resistant individual.

mAbs

journal-article